The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.
Aaron Ciechanover
When I campaign with seniors, it's always, 'Are you a Democrat or Republican?' But when I campaign on college campuses, they ask me where I stand on specific issues. I think Millennials are much less interested in conventional labels. One thing that's universal among Millennials is a distinct frustration with Washington, D.C.
Aaron Schock
I figure if people don't want to make the distinction between a Muslim and a terrorist, then why should I make a distinction between good scared white people and racists?
Aasif Mandvi
One of the chief tasks of any dialogue with the Gentile world is to prove that the distinction between anti-Semitism and anti-Zionism is not a distinction at all.
Abba Eban
Understand that legal and illegal are political, and often arbitrary, categorizations; use and abuse are medical, or clinical, distinctions.
Abbie Hoffman
Alfred Nobel stipulated that no distinction of race or colour will determine who received of his generosity.
Abdus Salam
Yes, I've heard of the 'Mad Men' comparisons, but I like to think 'The Hour' has its own distinctive voice. Although it is set in 1956, I have tried to give it a contemporary edge, and its themes of love, passion, romance, fury, professional jealousy, and personal failure are universal, I think.
Abi Morgan
One of my favorite albums in the world is Bruce Springsteen's 'Nebraska.' Each song has this very distinct character who has something profound to say.
Abigail Washburn
If it be true that our people represent a high percentage of mental vigor, the distinction is probably due, in some measure, to the extremely important part which Talmud studies have played in the spiritual life of the race.
Abraham Cahan
It would astonish if not amuse the older citizens to learn that I (a strange, friendless, uneducated, penniless boy, working at ten dollars per month) have been put down as the candidate of pride, wealth, and aristocratic family distinction.
Abraham Lincoln
I have my hopes, & very distinct ones, too, of one day getting cerebral phenomena such that I can put them into mathematical equations: in short, a law or laws for the mutual actions of the molecules of the brain (equivalent to the law of gravitation for the planetary & sideral world).
Ada Lovelace
And I think I have a distinct voice.
Adam Levine
As a writer, I find it very satisfying when a lyric suddenly ties together more neatly than you expected it to. But for the listener, hearing a good lyric is not generally as exciting as hearing a great beat or a great riff or a great melody or even a distinctive singing voice for the first time.
Adam Schlesinger
I remember vividly one distinct memory of arriving in Hong Kong and being the only blonde haired girl in this sea of international students, and thinking, 'Oh, my God. There's no hiding here.'
Adelaide Clemens
The type of cartooning that I think is generally referred to as 'alternative' or 'underground' is usually - the distinction is usually in terms of whether it's made by one person, the entire thing is done by one hand or more of a production line process, which is how the comics that we grew up reading were made.
Adrian Tomine
I have a very distinct memory of 'ExciteBike' and making my own courses. I had an obsession with that game.
AJ Lee
The one thing that is distinctive about America historically has been the fact that we are all able to engage in public discourse without the political becoming personal.
Ajit Pai
Katie Price is no exception. She, too, is - in a distinctive way - a philosopher. Partially, Katie Price's philosophy is one of extraordinary confidence. She is remarkable not for her looks or antics but because of her tremendous self-assurance and her unwillingness to be intimidated by criticism or failure.
Alain de Botton
Imagine maintaining 70 brands in a digital world - it is a nonsense. It is better to focus on a fewer, more distinct brands.
Alain Dehaze
We're not going the photography route. I think there is a real distinction between photos and images, and Flickr is for photos, and Instagram is for photos. You wouldn't put a filter on a meme; you'd put a filter on top of a photo that came from your camera.
Alan Schaaf
Palmares Tres is a society born out of a distinct, idiosyncratic utopian vision formed in the midst of an apocalypse. I would say the residents of Palmares Tres respect the strength of that history and their remarkable ability to rise from the ashes of the old world.
The distinction between the past, present and future is only a stubbornly persistent illusion.
Assuming that man has a distinct spiritual nature, a soul, why should it be thought unnatural that under appropriate conditions of maladjustment, his soul might die before his body does; or that his soul might die without his knowing it?
In Bosnian, there's no distinction in literature between fiction and nonfiction; there's no word describing that.
I think there's a fundamental distinction between character-driven movies that are just really lovely slice-of-life movies and character-driven movies that you remember 20 or 30 years later; the common denominator with the ones you remember is that they all have some really complicated emotional problem at their core.
The Awa are a distinctive-looking, diminutive forest people, smaller than any of the dozen other Amazon tribespeople I have met. Reduced size is adaptive in a rain forest. You can move around more easily and unobtrusively. Not only humans but other species are smaller in rain forests.
The idea that humanity is divided into these separate and distinct and disparate groups with clear boundaries has been disproven by science a long time ago, decades ago. Humanity really is more of a continuum, and that people belong on the same continuum and there are no clear breaks between these so-called races.
It's funny because I think that both France and Britain are known for their distinctive styles, and everyone says that France is so chic and elegant but I think, more than that, French women are renowned for dressing in what suits them.
I left my job as an editorial assistant with Katie Couric at CBS to start our company. I think Katie has said being at CBS was the worst time in her career. They were cutting back their news and interactive budget. I just had this very distinct feeling that I wasn't in the spring of something: I was in the late fall.
If the egotist is weak, his egotism is worthless. If the egotist is strong, acute, full of distinctive character, his egotism is precious, and remains a possession of the race.
Apart from a small minority, teenage boys fall into three distinct categories: macho, metro, or just plain muddled.
We like to make the distinction between immigrants we want and immigrants we don't want. They all share one thing, and that's the work ethic.
I'm distinct, really.
Again, most of the chief distinctions marked by economic terms are differences not of kind but of degree.
Intelligence is quickness to apprehend as distinct from ability, which is capacity to act wisely on the thing apprehended.
The arts equally have distinct departments, and unless photography has its own possibilities of expression, separate from those of the other arts, it is merely a process, not an art.
Although, at times, soccer is a challenge to mind, body, and spirit, fundamentally, the progression of the U.S. women's game and those who play it reflects a distinctively American culture, rooted in our struggle, shared aspiration, hard work and self-determination.
I think it is fine to have sports divided into men's and women's, just as it is fine to say a fifteen-year-old is incapable of consenting to sex. But we should recognize these are social distinctions based on biology, and not categories foisted upon us by nature.
I don't think I make much of a distinction between the 'real' and the 'fantastic.' They both seem to be threads in the same cloth as far as I'm concerned.
One of the most distinctive evolutionary features of human beings is our unusually long, protected childhood.
Having been built in the fashion I was as a child - created and then deflated - has left me with a distinct feeling of failure. Because I did not live up to my precocity, I experience it to be like a cross between a has-been and a never-was.
I think it's a false distinction to say that conversation and composition are separate. Because even as we speak, I'm seeing. Every interview is different, and I'm finding new ways to talk about ancient preoccupations. And I sometimes come on something that's immensely helpful and valuable. Plus I like the sensation of conversation.
The role of matriarch and patriarch are distinct, and in the King family, we have been blessed with strong examples of both.
For people like me, who have got their flags and wars mixed up, I think it should be pointed out that there may have been only one War of 1812, but there are four distinct versions of it - the American, the British, the Canadian, and the Native American.
My mother is black, from Grenada, so my blackness was always there, but It wasn't until I started hanging with the upperclassmen black actors at my high school that I really got my roots in being a black American, which is a distinctly different identity and experience.
For any sport to be sustainable, it cannot survive on government or corporate grants alone. The sporting ecosystem needs more investments from businesses, and businesses need to see the returns from their investment in sport. Cricket has achieved that distinction, but I feel a country of a billion-plus people cannot remain captive to one sport.
Nature has no principles. She makes no distinction between good and evil.
The distinction is large in my mind. The gay police captain is eventually going to be wearing hot pants and singing 'YMCA.' The police captain who happens to be gay is going to be a huge collection of personality characteristics and motivations.
Genocide begins, however improbably, in the conviction that classes of biological distinction indisputably sanction social and political discrimination.
King Lear alone among these plays has a distinct double action. Besides this, it is impossible, I think, from the point of view of construction, to regard the hero as the leading figure.
