The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.

Aaron Ciechanover

Future Ups Up

Aaron Ciechanover

Future Ups Up

When I campaign with seniors, it's always, 'Are you a Democrat or Republican?' But when I campaign on college campuses, they ask me where I stand on specific issues. I think Millennials are much less interested in conventional labels. One thing that's universal among Millennials is a distinct frustration with Washington, D.C.

Aaron Schock

You Wit Where

I figure if people don't want to make the distinction between a Muslim and a terrorist, then why should I make a distinction between good scared white people and racists?

Aasif Mandvi

Good Car Why

One of the chief tasks of any dialogue with the Gentile world is to prove that the distinction between anti-Semitism and anti-Zionism is not a distinction at all.

Abba Eban

World Wit Tis

Understand that legal and illegal are political, and often arbitrary, categorizations; use and abuse are medical, or clinical, distinctions.

Abbie Hoffman

Medical Legal Use

Alfred Nobel stipulated that no distinction of race or colour will determine who received of his generosity.

Abdus Salam

Will Who Tip

Yes, I've heard of the 'Mad Men' comparisons, but I like to think 'The Hour' has its own distinctive voice. Although it is set in 1956, I have tried to give it a contemporary edge, and its themes of love, passion, romance, fury, professional jealousy, and personal failure are universal, I think.

Abi Morgan

Men Love Jealousy

One of my favorite albums in the world is Bruce Springsteen's 'Nebraska.' Each song has this very distinct character who has something profound to say.

Abigail Washburn

Teen World Who

If it be true that our people represent a high percentage of mental vigor, the distinction is probably due, in some measure, to the extremely important part which Talmud studies have played in the spiritual life of the race.

Abraham Cahan

Men Life Art

It would astonish if not amuse the older citizens to learn that I (a strange, friendless, uneducated, penniless boy, working at ten dollars per month) have been put down as the candidate of pride, wealth, and aristocratic family distinction.

Abraham Lincoln

Work Family Zen

I have my hopes, & very distinct ones, too, of one day getting cerebral phenomena such that I can put them into mathematical equations: in short, a law or laws for the mutual actions of the molecules of the brain (equivalent to the law of gravitation for the planetary & sideral world).

Ada Lovelace

Men Hope World

And I think I have a distinct voice.

Adam Levine

Voice Tin Think

As a writer, I find it very satisfying when a lyric suddenly ties together more neatly than you expected it to. But for the listener, hearing a good lyric is not generally as exciting as hearing a great beat or a great riff or a great melody or even a distinctive singing voice for the first time.

Adam Schlesinger

Time Great Good

I remember vividly one distinct memory of arriving in Hong Kong and being the only blonde haired girl in this sea of international students, and thinking, 'Oh, my God. There's no hiding here.'

Adelaide Clemens

God Vivid Tin

The type of cartooning that I think is generally referred to as 'alternative' or 'underground' is usually - the distinction is usually in terms of whether it's made by one person, the entire thing is done by one hand or more of a production line process, which is how the comics that we grew up reading were made.

Adrian Tomine

Car Art Which

I have a very distinct memory of 'ExciteBike' and making my own courses. I had an obsession with that game.

AJ Lee

Wit Very Tin

The one thing that is distinctive about America historically has been the fact that we are all able to engage in public discourse without the political becoming personal.

Ajit Pai

Age Without Wit

Katie Price is no exception. She, too, is - in a distinctive way - a philosopher. Partially, Katie Price's philosophy is one of extraordinary confidence. She is remarkable not for her looks or antics but because of her tremendous self-assurance and her unwillingness to be intimidated by criticism or failure.

Alain de Botton

Men Failure Art

Imagine maintaining 70 brands in a digital world - it is a nonsense. It is better to focus on a fewer, more distinct brands.

Alain Dehaze

World Us Tin

We're not going the photography route. I think there is a real distinction between photos and images, and Flickr is for photos, and Instagram is for photos. You wouldn't put a filter on a meme; you'd put a filter on top of a photo that came from your camera.

Alan Schaaf

Age Your You

Palmares Tres is a society born out of a distinct, idiosyncratic utopian vision formed in the midst of an apocalypse. I would say the residents of Palmares Tres respect the strength of that history and their remarkable ability to rise from the ashes of the old world.

Alaya Dawn Johnson

The distinction between the past, present and future is only a stubbornly persistent illusion.

Albert Einstein

Assuming that man has a distinct spiritual nature, a soul, why should it be thought unnatural that under appropriate conditions of maladjustment, his soul might die before his body does; or that his soul might die without his knowing it?

Albert J. Nock

In Bosnian, there's no distinction in literature between fiction and nonfiction; there's no word describing that.

Aleksandar Hemon

I think there's a fundamental distinction between character-driven movies that are just really lovely slice-of-life movies and character-driven movies that you remember 20 or 30 years later; the common denominator with the ones you remember is that they all have some really complicated emotional problem at their core.

Alex Kurtzman

The Awa are a distinctive-looking, diminutive forest people, smaller than any of the dozen other Amazon tribespeople I have met. Reduced size is adaptive in a rain forest. You can move around more easily and unobtrusively. Not only humans but other species are smaller in rain forests.

Alex Shoumatoff

The idea that humanity is divided into these separate and distinct and disparate groups with clear boundaries has been disproven by science a long time ago, decades ago. Humanity really is more of a continuum, and that people belong on the same continuum and there are no clear breaks between these so-called races.

Alex Tizon

It's funny because I think that both France and Britain are known for their distinctive styles, and everyone says that France is so chic and elegant but I think, more than that, French women are renowned for dressing in what suits them.

Alexa Chung

I left my job as an editorial assistant with Katie Couric at CBS to start our company. I think Katie has said being at CBS was the worst time in her career. They were cutting back their news and interactive budget. I just had this very distinct feeling that I wasn't in the spring of something: I was in the late fall.

Alexa Hirschfeld

If the egotist is weak, his egotism is worthless. If the egotist is strong, acute, full of distinctive character, his egotism is precious, and remains a possession of the race.

Alexander Smith

Apart from a small minority, teenage boys fall into three distinct categories: macho, metro, or just plain muddled.

Alexandra Adornetto

We like to make the distinction between immigrants we want and immigrants we don't want. They all share one thing, and that's the work ethic.

Alexandra C. Pelosi

I'm distinct, really.

Alexei Sayle

Again, most of the chief distinctions marked by economic terms are differences not of kind but of degree.

Alfred Marshall

Intelligence is quickness to apprehend as distinct from ability, which is capacity to act wisely on the thing apprehended.

Alfred North Whitehead

The arts equally have distinct departments, and unless photography has its own possibilities of expression, separate from those of the other arts, it is merely a process, not an art.

Alfred Stieglitz

Although, at times, soccer is a challenge to mind, body, and spirit, fundamentally, the progression of the U.S. women's game and those who play it reflects a distinctively American culture, rooted in our struggle, shared aspiration, hard work and self-determination.

Ali Krieger

I think it is fine to have sports divided into men's and women's, just as it is fine to say a fifteen-year-old is incapable of consenting to sex. But we should recognize these are social distinctions based on biology, and not categories foisted upon us by nature.

Alice Dreger

I don't think I make much of a distinction between the 'real' and the 'fantastic.' They both seem to be threads in the same cloth as far as I'm concerned.

Alice Hoffman

One of the most distinctive evolutionary features of human beings is our unusually long, protected childhood.

Alison Gopnik

Having been built in the fashion I was as a child - created and then deflated - has left me with a distinct feeling of failure. Because I did not live up to my precocity, I experience it to be like a cross between a has-been and a never-was.

Alissa Quart

I think it's a false distinction to say that conversation and composition are separate. Because even as we speak, I'm seeing. Every interview is different, and I'm finding new ways to talk about ancient preoccupations. And I sometimes come on something that's immensely helpful and valuable. Plus I like the sensation of conversation.

Allan Gurganus

The role of matriarch and patriarch are distinct, and in the King family, we have been blessed with strong examples of both.

Alveda King

For people like me, who have got their flags and wars mixed up, I think it should be pointed out that there may have been only one War of 1812, but there are four distinct versions of it - the American, the British, the Canadian, and the Native American.

Amanda Foreman

My mother is black, from Grenada, so my blackness was always there, but It wasn't until I started hanging with the upperclassmen black actors at my high school that I really got my roots in being a black American, which is a distinctly different identity and experience.

Amanda Seales

For any sport to be sustainable, it cannot survive on government or corporate grants alone. The sporting ecosystem needs more investments from businesses, and businesses need to see the returns from their investment in sport. Cricket has achieved that distinction, but I feel a country of a billion-plus people cannot remain captive to one sport.

Anand Mahindra

Nature has no principles. She makes no distinction between good and evil.

Anatole France

The distinction is large in my mind. The gay police captain is eventually going to be wearing hot pants and singing 'YMCA.' The police captain who happens to be gay is going to be a huge collection of personality characteristics and motivations.

Andre Braugher

Genocide begins, however improbably, in the conviction that classes of biological distinction indisputably sanction social and political discrimination.

Andrea Dworkin

King Lear alone among these plays has a distinct double action. Besides this, it is impossible, I think, from the point of view of construction, to regard the hero as the leading figure.

Andrew Coyle Bradley