I feel in the depths of my soul that it is the highest, most sacred, and most irreversible part of my obligation to preserve the union of these states, although it may cost me my life.
Andrew Jackson
It's important to say that depression has biological underpinnings, and that while medications do not seem to create irreversible changes in the brain, repeated depressive episodes do.
Andrew Solomon
We have made mistakes. In our haste to do all things for all people, we did not foresee the full consequences of our actions. And when the people raised their voices, we didn't hear. But our deafness was only a temporary condition, and not an irreversible condition.
Barbara Jordan
I'm choosing not to accept the Trumpification of the GOP as an irreversible fact.
Bill Kristol
I believe we are on an irreversible trend toward more freedom and democracy - but that could change.
Dan Quayle
As far as I am concerned this referendum should settle the matter. I believe it will one way or another be decisive. Britain will not want to go through this again. On the other hand if we vote to leave, this really is irreversible.
David Cameron
What politicians want to create is irreversible change because when you leave office someone changes it back again.
Estelle Morris
Nothing in the world is irreversible, not even capitalism.
Fidel Castro
The death of Abdel Nasser on September 28, 1970, was an irreversible setback for Egypt.
Humans have changed ecosystems more rapidly and extensively than in any comparable period of time in human history, largely to meet rapidly growing demands for food, fresh water, timber, fiber and fuel. This has resulted in a substantial and largely irreversible loss in the diversity of life on Earth.
Gary Larson
Russians clearly perceive America's global influence as being in irreversible decline and American society shattered by major political, economic and ideological crises.
Ivan Krastev
Unfortunately, some of our poor choices are irreversible, but many are not. Often, we can change course and get back on the right track.
James E. Faust
The revolutionary process by which all books, old and new, in all languages, will soon be available digitally, at practically no cost for storage and delivery, to a radically decentralized world-wide market at the click of a mouse, is irreversible.
Jason Epstein
From that moment on, there will be an irreversible process to separate Quebec from Canada.
Jean Charest
We are of the opinion that an important and irreversible process is taking place among the white population. Just as with the blacks, the whites, too, are currently overcoming a psychological barrier.
Joe Slovo
One thing is obvious: Our policy, which is directed at making the country ungovernable, has started to bear fruit. The process that has been initiated is irreversible.
Our objectives are socialist. That means an irreversible shift in the balance of power and wealth in favour of working people.
John McDonnell
If a child in its first thousand days - from conception to two years old - does not have adequate nutrition, the damage is irreversible.
Josette Sheeran
I say that building peace is like building a cathedral. You have to have a solid base, and then you do it brick by brick. But the process is irreversible. There's no way back.
Juan Manuel Santos
We have chosen to bring future generations into this world of rising seas and warming temperatures, droughts and floods, heat waves and wildfires, a world in which one in four mammals and one in eight birds are at risk of disappearing forever. While the damage we've done is irreversible, that doesn't give us the right to do nothing.
Leonor Varela
Beto is not a transformational political saviour. He is a hypocritical hack who's so lightweight he goes where the wind blows even if it tumbles him and the economy to irreversible hell.
Europe must dissipate any doubts over the euro, affirm that the euro is an irreversible project and act in consequence.
I used to write on a big old couch, but I gave that away. I was wise enough to give it to my son, so if it turns out that the couch was essential to my work, at least the decision to be rid of it is not irreversible.
A Soviet man is a product of invisible changes, degradation and progressive deformation. Breaking the chain of those changes is hard. Perhaps they are irreversible.
A reactionary is someone who wants to return to a previous state - that's never a possibility in my books. For me, everything's irreversible in the life of a society, as well as an individual's.
Without the U.S. leading the way in trade negotiations, we likely will see irreversible damage to our environment and widespread abuse of labor and human rights, all while we lose out on the opportunity to expand our economy and create jobs.
Irreversible is not glamorous at all. I try to do different things because I want to grow as an actress and I like to take risks.
I like a movie that brings out many discussions. From my experience, every time I have done movies, they create this kind of situation. Like 'Irreversible,' 'The Passion of the Christ,' 'Malena'; it's so interesting. I like to explore the dark side of humanity. That's why I'm an actor.
In the 00s, it was often claimed that political apathy had replaced political participation. Membership of political parties and electoral turnout were both said to be in irreversible decline.
My favorite film score is the one Thomas Bangalter created for 'Irreversible.' The soundtrack absolutely defines the daymare-into-nightmare feeling you get from the film.
The particular aspect of time that I'm interested in is the arrow of time: the fact that the past is different from the future. We remember the past but we don't remember the future. There are irreversible processes. There are things that happen, like you turn an egg into an omelet, but you can't turn an omelet into an egg.
The security fence is reversible. Human lives are irreversible.
I have a statement on the Social Security. A lot of people approaching that age have either already retired on pensions or have made irreversible plans to retire very soon... I consider it a breach of faith to renege on that promise. It is a rotten thing to do.
Comebacks don't seem likely when your back is up against the wall and your hope is depleted. But if you will stay the course, you will discover God's power to reverse the irreversible in your life.
If left unchecked, global change will create violent conflict, torrential storms, shrinking coastlines, and irreversible catastrophe.
What I think I'm perceived as in France is, like, I'm this leading man always doing strange movies because most of the movies I did, like 'Irreversible' or 'Brotherhood of the Wolf' and a bunch of others, and even in France, they always come out as a particular movie, not like the typical French kind of movies that people know most of the time.
Is it 10 years, 20, 50 before we reach that tipping point where climate change becomes irreversible? Nobody can know. There's clearly a probability distribution. We need to ensure this planet, and we need to do it quickly.
