Reticulocytes are terminally differentiating red blood cells that do not contain lysosome. Therefore, it was postulated that the degradation of hemoglobin in these cells is mediated by a non-lysosomal machinery.
Aaron Ciechanover
The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.
The people who abandon Jihad fall a victim to humility and degradation.
Abu Bakr
Man cannot degrade woman without himself falling into degradation; he cannot elevate her without at the same time elevating himself.
Alexander Walker
I suppose one has a greater sense of intellectual degradation after an interview with a doctor than from any human experience.
Alice James
One has a greater sense of degradation after an interview with a doctor than from any human experience.
It was a feeling of loyalty to our own sex and an enthusiasm to have every degradation that was put upon our sex removed.
Alice Paul
I believe we need to attract a new generation of the best and brightest to public service and I believe that government can be a source of inspiration, not degradation.
Andrew Cuomo
War is a blessing compared with national degradation.
Andrew Jackson
Judging by my degradation in the last 24 hours, I'll be surprised if I make it to Tuesday.
Aron Ralston
Grave security concerns can arise as a result of demographic trends, chronic poverty, economic inequality, environmental degradation, pandemic diseases, organized crime, repressive governance and other developments no state can control alone. Arms can't address such concerns.
Ban Ki-moon
The degradation of natural resources such as forests and freshwater has removed much of the resilience that societies formerly enjoyed.
Barry Gardiner
Reclaiming the word 'fat' was the most empowering step in my progress. I stopped using it for insult or degradation and instead replaced it with truth, because the truth is that I am fat, and that's ok. So now when someone calls me fat, I agree, whereas before I would get embarrassed and emotional.
Beth Ditto
In the case of 'Chernobyl,' we're telling a story of a government that runs on lies the way cars run on fuel, and there are people who ultimately end up paying the price for those lies - and a certain culture of denial is in place, and the degradation of expertise is in place.
Craig Mazin
I think I would much rather push the boundaries of the degradation that the characters face.
Dave Rowntree
People who need therapy are in Afghanistan. They've seen horrible human cruelty and degradation, but they don't have time or the money for therapy.
David Chase
With 'Nostromo', Joseph Conrad said that he had wanted to write a novel about the degradation of an idea. That's what we wanted to show in the case of Dustin Hoffman's character, Bernstein.
David Milch
We dragged the National Health Service from the depths of degradation. I've got a United Nations heart bypass to prove it and it was done by a Syrian cardiologist, a Malaysian surgeon, a Dutch doctor and a Nigerian registrar.
Dennis Skinner
Reducing and removing greenhouse gas emissions spares our planet from the well-documented degradation that we are witnessing on a global basis.
Dick Durbin
The more I think on the present condition of woman, the more am I oppressed with the reality of their degradation.
Elizabeth Cady Stanton
We found nothing grand in the history of the Jews nor in the morals inculcated in the Pentateuch. I know of no other books that so fully teach the subjection and degradation of woman.
The road back from degradation begins with self-awareness - and sometimes, as in 'Phone Booth,' change can begin with a single phone call.
But it will be said that the husband provides for the wife, or in other words, he feeds, clothes and shelters her! I wish I had the power to make every one before me fully realize the degradation contained in that idea.
What I loathe is the multi-national conglomerates who must take responsibility for the degradation and pollution of so much of our landscape with their factory farming and greed.
The national debate on health care once centered on improving access to quality care, yet the effect of Obamacare will be the exact opposite, resulting in the shameful degradation of care for the neediest individuals.
The audience too should be respected by being presented with a film as they remember it, and for those who have not seen it, as it was intended to be seen. Anything less is a degradation of the film and its audience.
Unless we practice conservation, those who come after us will have to pay the price of misery, degradation, and failure for the progress and prosperity of our day.
The ocean is our planet's life support system, yet in my travels and at home, I've seen its degradation firsthand.
The fundamental driving force for me is to create a change in the world we live in... It is about exploitation, plundering and degradation. I have a small possibility to participate in the resistance. Most of the things that I do are part of a resistance, a form of solidarity work.
I have come to the conclusion that it's a waste of time to have too much pride in anything. Perhaps it's good to have a sense of duty, a jealous zeal to protect or improve, but pride ultimately is only that which stands vulnerable to offense and degradation.
Dramas about addiction can be exciting to watch. And then dispiriting. Exciting because degradation is fascinating to follow from the relative safety and smugness of an 'appropriate' life, and dispiriting because if all that sad mayhem can happen to this or that character, what's to keep it from happening to me or you?
For the record, I am sticking with my claim that the simultaneous degradation of air quality, water quality, water supply, food safety, soil quality, and other environment-related variables is the main challenge to China's continued development.
People are suspicious of science. They see it as being responsible for problems like the degradation of our climate. There is also a strand in society that says physics is terribly hard.
Land degradation did not start with chemical agriculture. But chemical agriculture offered new tools for annihilation.
I think it's important to understand that in the big historical context of things, there has been land degradation from civilisation since the beginning of history. I mean, the Rajputana desert in India is a manmade desert caused by overgrazing.
We see evidence that lakes and forests and wetlands can have different equilibria - so you have a savanna system that may be stable and thriving, but it can also tip over and become an arid steppe if pushed too far by warming, land degradation, and biodiversity loss.
As a southerner born after the epic events of the civil rights movement, I've always wondered how on earth people of good will could have conceivably lived with Jim Crow - with the daily degradations, the lynchings in plain sight, and, as the movement gathered force, with the fire hoses and the police dogs and the billy clubs.
Presidents and prime ministers, whether they live in the rich or the poor world, are insulated and isolated from the devastating impact of global poverty. They read the statistics, but they rarely witness at first hand the misery and degradation of life on a dollar a day.
So long as the most vulnerable people in our population are consigned to places that the rest of us will always shun and flee and view with fear, I am afraid that educational denial, medical and economic devastation, and aesthetic degradation will be inevitable.
Food and the way we grow it and produce it are a major cause of environmental degradation.
Abasement, degradation is simply the manner of life of the man who has refused to be what it is his duty to be.
Man, in spite of his fatal degradation, bears always the evident marks of his divine origin, in that every universal belief is always more or less true.
From my perspective, to really be ready, we can't afford to have these deep degradations in readiness associated with personnel turbulence post-deployment.
My background is degradation and sloth, mostly.
Today, the degradation of the inner life is symbolized by the fact that the only place sacred from interruption is the private toilet.
The world has never yet seen a truly great and virtuous nation because in the degradation of woman the very fountains of life are poisoned at their source.
Ours is one continued struggle against degradation sought to be inflicted upon us by the European, who desire to degrade us to the level of the raw Kaffir, whose occupation is hunting and whose sole ambition is to collect a certain number of cattle to buy a wife with, and then pass his life in indolence and nakedness.
From a planning perspective, economic degradation begets environmental degradation, which begets social degradation.
Autocratic power requires the degradation of moral authority - not the capture of moral high ground.
We have seen a degradation from the highest levels of authority politically in this nation, including through the department of justice, for the rule of law.
