Reticulocytes are terminally differentiating red blood cells that do not contain lysosome. Therefore, it was postulated that the degradation of hemoglobin in these cells is mediated by a non-lysosomal machinery.
Aaron Ciechanover
The development of methods to monitor protein dynamics in cells together with the discovery of specific and general lysosomal inhibitors have resulted in the identification of different classes of cellular proteins, long- and short-lived, and the findings of the differential effects of the inhibitors on these groups.
There are over 7,000 different types of proteins in typical eukaryotic cells; the total number depends on the cell class and function.
Ada Yonath
At the end of the 1970s, I was a young researcher at the Weizmann Institute with an ambitious plan to shed light on one of the major outstanding questions concerning living cells: the process of protein biosynthesis.
Henrietta Lacks' cells are immortal. They are known as the HeLa cell line, and they have become deeply involved in all sorts of medical and genetic research - sometimes in the most unexpected ways.
Adam Curtis
One thing I always noticed out of Bill Parcells is that he always wanted a good class of blue-collar, hardworking guys that he felt like he could win games with that way... When the difficult times came about he knew who was going to perform.
Adam Vinatieri
Coach Parcells challenged me a lot in my rookie year, and not just in games. Almost every day in practice, he'd stand right beside me as he called for the field-goal team to take the field.
I first learned about kicking under pressure in 1996, my rookie year with the Patriots. I was signed as a free agent by a team that already had Matt Bahr, one of the best kickers around. To win the job, I had to show coach Bill Parcells that I could make kicks when they counted. That process started in training camp.
These little grey cells. It is up to them.
Agatha Christie
Man, like other organisms, is so perfectly coordinated that he may easily forget, whether awake or asleep, that he is a colony of cells in action, and that it is the cells which achieve, through him, what he has the illusion of accomplishing himself.
Albert Claude
It is the cells which create and maintain in us, during the span of our lives, our will to live and survive, to search and experiment, and to struggle.
Is it absurd to imagine that our social behavior, from amoeba to man, is also planned and dictated, from stored information, by the cells? And that the time has come for men to be entrusted with the task, through heroic efforts, of bringing life to other worlds?
We must move away from our dependency on fossil fuels, and I am glad that GM has invested over $1 billion in hydrogen fuel cells cars to meet this goal.
Albert Wynn
To become a celebrity, a name - and I've actually met some that speak of themselves in the third person - it's scary. They become an object, not a human, complex, questioning thing where the cells are always changing.
Alejandro Gonzalez Inarritu
What I see in science is a lot of imagination referring to things that are fundamental to what we are. Our cells, our history, our future, our place in the universe, our lack of place in the universe. That's poetry as far as I'm concerned.
Alex Garland
We don't notice that our cells are turning over all the time. You get a completely new composition of cells every seven years, and on the surface, or subjectively, it looks as though you're the same for seven years. It's like a ground - it looks stable, but beneath it, everything is shifting all the time. It's exciting and dangerous.
Alexandra Kleeman
The best standardisation committee in the world is nature herself, but in nature standardisation occurs mainly in connection with the smallest possible units: cells. The result is millions of flexible combinations in which one never encounters the stereotyped.
Alvar Aalto
We are, each one of us, not just defined by the arrangement of protein molecules in our cells, but also by the things we call our own.
Andre Aciman
Ideas not coupled with action never become bigger than the brain cells they occupied.
Arnold H. Glasow
Biology is the most powerful technology ever created. DNA is software, protein are hardware, cells are factories.
Arvind Gupta
I have lived in other cities but been inside of only one. I once wore all the windows of Chicago and all its doorways on a key ring. Salons, mansions, alleys, courtrooms, depots, factories, hotels, police cells, the lake front, the rooftops and the sidewalks were my haberdashery.
Those revolutionaries who have, by chance, escaped the gallows should live and show to the world that they cannot only embrace gallows for the ideal but also bear the worst type of tortures in the dark, dingy prison cells.
For example, a breakthrough in better batteries could supplant hydrogen. Better solar cells could replace or win out in this race to the fuel of the future. Those, I see, as the three big competitors: hydrogen, solar cells and then better batteries.
I'm glad you can't talk on your cells while the plane is in the air. That would drive me crazy.
By weight, you are more human than bacteria, because your cells are bigger, but by numbers, it's not even close.
It's incorrect to think of bacteria as these asocial, single cells. They are individual cells, but they act in communities, exactly the way people do.
Bacteria are single-celled organisms. Bacteria are the model organisms for everything that we know in higher organisms. There are 10 times more bacterial cells in you or on you than human cells.
In my lab, we are always thinking about how cells, bacterial cells, can talk to each other and then organize themselves into enormous groups that function in unison.
We're scientists; we're curious about how nature works, but we're also do-gooders. It's fantastic to think that the same experiments we'd do to understand how information gets into cells could have a practical side to them, too.
If you have pendulum clocks on the wall and start them all at different times, after a while the pendulums will all swing in synchronicity. The same thing happens with heart cells in a Petri dish: They start beating in rhythm even when they're not touching one another.
One of the first papers I wrote at the University of Wisconsin, in 1977, was on stem cells. I realized that if I changed the environment that these cells were in, I could turn the cells into bone, and if I changed the environment a bit more, they would form fat cells.
We keep thinking that the human is evolving. No, the human has evolved to its extent. What's happening now is the organization of humans: just like cells organize to form people, people are organizing to form humanity.
My fat cells have a memory like Einstein! I'm proof that surgery is not a magic potion. There are many ways to sabotage it.
Actresses can get outrageously precious about the way they look. That's not what life's about. If you starve yourself to the point where your brain cells shrivel, you will never do good work. And if you're overly conscious of your arms flapping in the wind, how can you look the other actor in the eye to respond to them?
The theologians have recognized that the ideal is the imitation of God. If we be a part of such an organic thing, this thing is God to us, as I am God to the cells that compose me.
The cell is a city of production centres, each part working away like mad, and it's co-ordinated. Six trillion cells in a body - you can't help but be moved.
In 1880 at the Military Hospital at Constantine, I discovered, on the edges of the pigmented spherical bodies in the blood of a patient suffering from malaria, filiform elements resembling flagellae which were moving very rapidly, displacing the neighbouring red cells.
It's been said that mistletoe extract enhances immune function, which increases the production of the immune cells. When administered as a form of therapy for cancer, the extracts are given by injection under the skin, into a vein or directly into a tumor.
Working out is incredibly boring. I swear it's true that the bigger your muscles get, the fewer brain cells you have.
The possibility that lysosomes might accidentally become ruptured under certain conditions, and kill or injure their host-cells as a result, was considered right after we got our first clues to the existence of these particles.
We are sick because our cells are sick.
China has national security laws that compel Chinese companies to provide the government with information and access at their government's request. And virtually all Chinese companies of any size are required to have Communist Party 'cells' inside them, to make sure the companies stay in line with the party's principles and policies.
I had just finished playing a doctor in Doctors' and I had had to tell somebody that they had cancer. In that moment I thought, He's doing what I did!' We sat down and he said, I'm sorry, Mr. Timothy, but I've got bad news.' I thought, Oh!' He told me that they had found cancerous cells, but not a lot.
One day between takes on the 'Oz' set, I went into one of the cells and laid down and dozed off. When I woke up, I thought I was back in a federal pen. But I did my time, and today no one is more of a free man than Chuck Zito.
Just when your ovaries should be brimming with youthful follicles, cancerous cells overtook mine, threatening to end my fertility and potentially my life.
It is true you cannot eat freedom and you cannot power machinery with democracy. But then neither can political prisoners turn on the light in the cells of a dictatorship.
Cells will die in minutes to days if they lack their genetic information system. They will not evolve, they will not replicate, and they will not live.
We have 200 trillion cells, and the outcome of each of them is almost 100 percent genetically determined. And that's what our experiment with the first synthetic genome proves, at least in the case of really simple bacteria. It's the interactions of all those separate genetic units that give us the physiology that we see.
When you think of all the things that are made from oil or in the chemical industry, if in the future we could find cells to replace most of those processes, the ideal way would be to do it by direct design.
Synthetic biology can help address key challenges facing the planet and its population. Research in synthetic biology may lead to new things such as programmed cells that self-assemble at the sites of disease to repair damage.
