The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.
Aaron Ciechanover
Steve Jobs is the most epic entrepreneur of all time. He served as a guiding light for any emerging businessperson who wanted to learn how things should get done. He'll be looked at as one of the best business leaders of all time, and certainly one of the best tech entrepreneurs.
Aaron Levie
I talk to myself all the time - it's something my children have observed in the car.
Abi Morgan
My mom didn't ever think I would take to acting because I was a very shy, very reserved kind of child. But obviously, something changed!
Abigail Breslin
Do not follow vain desires; for verily he who prospers is preserved from lust, greed and anger.
Abu Bakr
The idea of elegance and aristocratic indulgence of an ocean cruise was born out of the image of the rich men and women who ruled the British Empire slowly sailing to India and the Far East while sipping gin and tonic on deck - served by men in white jackets.
Adam Curtis
I loved being in the Marine Corps, I loved my job in the Marine Corps, and I loved the people I served with. It's one of the best things I've had a chance to do.
Adam Driver
I served in the Israeli Navy, and it's not an easy thing.
Adam Neumann
When I signed with Ring of Honor, looking back now, I don't think I deserved it.
Adam Page
All of the actors that have served to me as inspiration over the years have been those more associated with dramatic work who have, in turn, been able to embody their characters and lose themselves in those characters that they create.
Adhir Kalyan
We travel together, passengers on a little spaceship, dependent on its vulnerable reserves of air and soil, all committed, for our safety, to its security and peace. Preserved from annihilation only by the care, the work and the love we give our fragile craft.
Adlai Stevenson I
My father was a diplomat and served as Pakistan's ambassador to 14 countries. I was born in London and grew up there and studied and lived in a hostel throughout in London and became a barrister.
Adnan Sami
It only works because we still amuse each other. After we have been working with other people, it is so refreshing to laugh unreservedly when we are back together again.
Adrian Edmondson
Even though I'm usually not conscious of it, I think drawing has always served a sort of therapeutic purpose in my life. There's something about the process of translating the messy chaos of real life into a clean, simple drawing that's always been comforting to me.
Adrian Tomine
I'm Japanese, but restaurants in my hometown served the most sanitized versions of California rolls. I grew up eating a lot of Japanese food at home that my parents or grandparents made.
Being anonymous is a great luxury. It's a big loss to lose that. Mostly, the loss is the ability to observe others without being observed yourself. And as an actor, that is your key tool.
Adrien Brody
I've always been interested in oral traditions and mythological stories and legends from antiquity that have to do with nature, attempts to explain mysterious or puzzling, or very striking phenomena from nature. Things that people observed or heard about in nature.
Adrienne Mayor
It's my personality to be more quiet and reserved. I'm not going out every night to multiple things. I prefer to stay in and be with my children and do Spanish homework to make sure they get a good grade the next day.
Aerin Lauder
I've heard from other artists that people are a little bit more reserved in Northern Europe, which comes across at concerts, where the audience may be quieter. So this means less hecklers, but maybe it also means that people may not be as open about how they felt. I'm not so sure this is especially true of Denmark, but it's what I've heard.
Agnes Obel
To this day, I like the version of movies that don't have the curse words. I'm very reserved that way.
AJ Lee
Kendrick Lamar is a phenomenal artist whose work has served as a catalyst to raise a new level of consciousness for this generation. His message challenges the status quo and motivates listeners to rethink our society's institutions.
I dedicated my career to really working in under-served communities and really just being in the trenches.
Including my nine years as a student, the majority of my life has been at Hokkaido University. After my retirement from the university in 1994, I served at two private universities in Okayama Prefecture - Okayama University of Science and Kurashiki University of Science and the Arts - before retiring from university work in 2002.
The greatest compliment I get about my writing is when people say, 'How did you know so much about me?' And of course, the answer is very simple: 'I just observed myself without sentimentality.'
I think maybe the English don't want to try something and look stupid, because they are a bit reserved.
Before holding elective office - 12 years in the Wyoming House of Representatives and 18 years in the U.S. Senate - I served a different type of time. I was on probation for a federal offense committed as a teenager.
Rather than serving in the U.S. Senate for almost 20 years or having so many other wonderful life experiences, I could have served a longer sentence in prison for some of the stupid, reckless things I did as a teenager.
As a lifelong Republican who served in the Army in Germany, I believe it is critical that we review - and overturn - the ban on gay service in the military. I voted for 'don't ask, don't tell.' But much has changed since 1993. My thinking shifted when I read that the military was firing translators because they are gay.
I served three terms in the U.S. Senate and was co-chairman of the National Commission on Fiscal Responsibility and Reform in 2010. So I know a bit about how Washington operates, and I have had plenty of experience doing the work of running for office.
Throughout my career I have done it my way and used my stubborn streak. I thought the best way to captain was to shut out all the noise - I did it with my batting and thought 'that has served me well, so why change it?'
When I was about to turn 50, I went into a kind of personal revision and observed my own priorities and what led those priorities in my life. And many things that, in a way, were profound.
My father had a difficult relationship with success, maybe because he never obtained it. But he was very wise about it because he observed how you can become rotten fruit once you get power.
Some would suggest that there has been a dramatic change in our perception of the world and ourselves within the world. Others have observed that there has been an almost complete about-face in a relatively short span of time.
I have a great deal of empathy for anyone who's having a hard time. I believe this ability to see another's viewpoint has served me well as a writer.
My reasons for becoming a chef are somewhat of a cliche. I always loved to eat but it was watching my parents cook that really served as the impetus for my career choice.
To the best of my knowledge and of my effort, every lineage statement within 'Roots' is from either my African or American families' carefully preserved oral history, much of which I have been able conventionally to corroborate with documents.
The obsessive focus on a college degree has served neither taxpayers nor students well. Only 35 percent of students starting a four-year degree program will graduate within four years, and less than 60 percent will graduate within six years. Students who haven't graduated within six years probably never will.
I've certainly had many more opportunities than I deserved, but luckily enough I ended up making the right choices.
Praise undeserved, is satire in disguise.
When you're in the public eye, we all feel like we're constantly observed, so we don't let things out. Anger, sadness, happiness - when does that come out? Maybe when you're in traffic, because you're in the safety of your little metallic bubble.
Soldiers, I had lately like to have been taken from you by the attempt of a few desperate men, but by the grace and providence of the gods, I am still preserved.
Since 2008, I have been a Foreign Area Officer specializing in Eurasia. In this role, I have served in the United States' embassies in Kiev, Ukraine and Moscow, Russia.
Millennials give comics the kind of adulation past generations reserved for musicians. We respect Lady Gaga. But we'll travel hundreds of miles to touch the hem of Jon Stewart's robe.
I knew that our community needed a very clear voice. and I think we deserved representation that rejected lobbyist funds and put our voters and our community first.
Public schools in the late '80s and early '90s were a total mess... we felt that if I was going to have a good educational option in my life, I would have to go to a public school district that actually served its children.
When we put $4 billion into the U.S. economy, they were OK with this. When we preserved jobs in Dearborn, or preserved jobs in Columbus, or preserved jobs in Pennsylvania, everyone was happy.
Liberty cannot be preserved, if the manners of the people are corrupted.
I'm more interested in character than events. I've observed that about myself as a writer. I find events, even the most dramatic sort, not to be such fertile ground.
Salem houses present to you a serene and dignified front, gracious yet reserved, not thrusting forward their choicest treasures to the eyes of passing strangers; but behind the walls of the houses, enclosed from public view, lie cherished gardens, full of the beauty of life.
It seems that humans have been enjoying the taste and health benefits of blackberries for thousands of years. Gathered blackberries have been found at Neolithic sites, while a preserved iron age bog body, known as Haraldskaer Woman, provides definite evidence of blackberry ingestion.