I miss her in my bones. I was her big brother. I was supposed to protect her - I could not... It very nearly destroyed me.

I think it's your duty to overcome what you inherit in life.

As you wrestle with life... You're going to come out on the other end healed... I've fallen short sometimes, and I've risen pretty high a few times.

As a Christian, we always fail because we can't become Christ. But I can try to at least emulate the best qualities, even if I may fall short.

For every story you hear that's tragic, there's another that's equally tragic or more so. I think you come to look at it as part of life.

It takes a very strange person to enjoy fame, with all the by-products that come with it. It's not necessarily a thrill.

I became an actor, and because I had success as an actor, I became famous. I was acting for quite a while before I got famous; television made me famous. I guess that it's television that is responsible for everybody's desire to be famous.

Apologizes are pointless, regrets come too late. What matters is you can move, on you can grow.

No day-to-day mishaps or indignities can really compromise your sense of self after you've survived a deep tragedy.

Iago is one of the most liked characters in Shakespeare's canon, and he's the most evil, most extraordinarily manipulative person in history. He says the worst, most politically incorrect things, even for the time the play is set in - and yet audiences adore that character.

Actors are observers of human life, of human behavior.

I like audiences and performing and, you know... applause!

Frasier will always hold a special place in my heart. He's a great character I Ioved playing, and he's still a wonderful part of my life. But he was a lot of work!

I can't say it was challenging for me to shake the image of Frasier. I've been fortunate to have had a very interesting career since the series ended. I think the turning point for me was the show, 'Boss.'

I had a kind of romantic notion about being a Hollywood Errol Flynn type.

Gosh, I think faith is a wonderful thing. And I even think religion's a wonderful thing. I know a lot of people want to say, 'Religion's the only reason that man has had any trouble at all,' but you know what? World War I and World War II were not fought because of religious reasons.

Some of the greatest achievements ever have been achieved as a result of the Church. The Catholic Church. I'm not Catholic but yeah, the Church, for instance, you take a walk through the Vatican, and to your right is the double helix staircase built, I think, in 1138 or something.

All of the great music ever written is based upon the Mass. I mean, it's pretty extraordinary stuff, and I think it's done the world some good. And if you take a look at some of the mosques in the world, it calls you to worship the kind of beauty that's in there.

There was one thing I loved a little bit more than surfing - and that was acting.

Different things made 'Cheers' and 'Frasier' special. Both of them, though, were honest. It was the old Shakespeare thing: Hold the mirror up to life.

There's almost nothing better than a baguette and a pound of salami.

'Frasier' works because we stay focused on the idea that - how he continues to grow. It is not that you are really - the mission is not to try to keep him fresh; the idea is if you naturally put a character in a situation that demands growth of him, then he will remain fresh.

I think of houses as having their own personality.

I think it's important to approach a house in a way that's reflective of the original environment. Maybe I'm a sentimentalist, but I think that certain geographies call out for certain architecture. I like residences that reflect their place.

The first thing I did on television was a PBS thing where I played a priest. It was a Walt Whitman or Carl Sandburg story - I can't quite remember - but I was a turn-of-the-20th-century priest kind of guy. Never saw it; don't know if I was any good or not.

I thought 'Back To You' was a good show. The writers' strike really kind of put an end to that, though, honestly. There were a couple of factors involved, but to start a show and then to have it disappear and not come back for that long... it's just bad form.

I know a lot of people who've lost their siblings and blame themselves.

I'm a walk-on guy. When the director says, 'Action,' I'm on.

I had a kind of romantic notion about being a Hollywood Errol Flynn type. Honestly, I did not get into a lot of bar brawls - but I was always willing to. About the only thing missing from my story is that I haven't had a full knock-down fight in the middle of the Polo Lounge.

I don't really want to go into it, because whenever I say anything about my past now, it becomes a pissing match... but I realised that I had acquiesced, in my 40s, to an idea of 'You know what, maybe this thing that you wanted in your life, maybe it just wasn't important.'

I've said nice things about the people I was with before, but that's what you do.